产品货号：
GS4559
中文名称：
重组小鼠IL-7
英文名称：
Recombinant Murine Interleukin-7
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 14.9kDa,a single non-glycosylated polypeptide chain containing 129 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-7(IL-7)is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus.The protein signals through the IL-7 receptor,which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain.IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells,T cells and NK cells.Murine IL-7 has approximately 65%and 88%amino acid sequence identity with human and rat IL-7 and both proteins exhibit cross-species activity.IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠IL-7，IL-7, Murine，Recombinant Murine Interleukin-7
储存条件：冷冻（-20℃）
概述
Interleukin-7(IL-7)is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus.The protein signals through the IL-7 receptor,which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain.IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells,T cells and NK cells.Murine IL-7 has approximately 65%and 88%amino acid sequence identity with human and rat IL-7 and both proteins exhibit cross-species activity.IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞96%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 0.2ng/ml,corresponding to a specific activity of>5.0×106 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4,2%trehalose. |
| 内毒素 | Less than 1 EU/μg of rMuIL-7 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | ECHIKDKEGK AYESVLMISI DELDKMTGTD SNCPNNEPNF FRKHVCDDTK EAAFLNRAAR KLKQFLKMNI SEEFNVHLLT VSQGTQTLVN CTSKEEKNVK EQKKNDACFL KRLLREIKTC WNKILKGSI |
相关搜索：重组小鼠IL-7，IL-7, Murine，Recombinant Murine Interleukin-7